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Do washed irradiated red blood cells with a balanced solution improve the quality of the priming in cardiopulmonary bypass for neonates and infants?

Do washed irradiated red blood cells with a balanced solution improve the quality of the priming in cardiopulmonary bypass for neonates and infants? - Washing red donor bloodcells for CPB (Cardio Pulmonary Bypass)

Status
Unknown
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON32940
Enrollment
60
Registered
2009-10-26
Start date
Unknown
Completion date
Unknown
Last updated
2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Quality of red bloodcells

Interventions

Donor red blood cells (pre-washed group) will be washed by a cellsaver before using it in the prime of the cardiopulmonary bypass circuit.

Sponsors

Erasmus MC, Universitair Medisch Centrum Rotterdam
Lead Sponsor

Eligibility

Age
2 Years to 11 Years

Inclusion criteria

Inclusion criteria: Neonates and infants with a bodyweight of

Exclusion criteria

Exclusion criteria: Hepatic insufficienty Renal insufficiency Procedures with deep hypothermic circulatory arrest Procedures with a prolonged low flow technique Infants with a body weight > =20 kg Emergency procedures

Design outcomes

Primary

MeasureTime frame
Hemoglobin, hematocrit, platelet count, potassium, sodium, chlorine, lactate, free hemoglobin and blood gasses will be measured by standard protocol.

Secondary

MeasureTime frame
Ventricular function assessment will be measured by routine intra-operative Tran esophageal echocardiography and by thermo dilution. Hospitalization and ventilation period will be noted.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)