niet van toepassing n.v.t.
Conditions
Interventions
We will use single-pulse TMS during the anticipitory phase of the experiment,
and we will measure brain activity with help of EEG. Earlier studies have shown
the effectivity of this set-up, using lo
Sponsors
Radboud Universiteit Nijmegen
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Right-handed individuals, with normal or corrected-to-normal vision and no history of neurological or psychological disorders are included.
Exclusion criteria
Exclusion criteria: - Pacemaker - Metal parts in head or mouth - History of brain surgery - History of epilepsy or first-grade family member with epilepsy - Psychological or neurological disorder - Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The effect of TMS on the three stimulation sites will be assessed using concurrently measured EEG. We will test whether stimulation to LOC, OFA, and vertex differentially affect the TMS-induced evoked potential, as a function of predictability and attention. We hypothesize that predictability will lead to a strengthening of backward connectivity (Friston 2005), in a stimulus-specific manner and irrespective of the attentional set. Attention is hypothesized to have an additive effect on backward connection strength that does not interact with predictability (Morishima, Akaishi et al. 2009). | — |
Secondary
| Measure | Time frame |
|---|---|
| We will also measure behavioural performance (reaction times and error rates) during the experiment, as the subjects task is to respond as quickly as possible to one of the two shapes. We will probe whether, at the low intensities of TMS applied, the RT gain for anticipated stimuli will be diminished or abolished by TMS intervention. | — |
Countries
Netherlands
Outcome results
None listed