dwarslaesie spinal cord injury
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Sint Radboud
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Spinal cord injury: - complete thoracic or cervical spinal cord lesion - ability to perform arm-crank exercise;Controls: - healthy
Exclusion criteria
Exclusion criteria: All subjects: - cardiovascular diseases - medication known to interfere with the thermoregulation - To prevent problems with using the telemetry pill we use the following exclusion criteria: 1. obstructive disease of the gastro-intestinal tract, including diverticulitis and inflammatory bowel disease 2. previous gastrointestinal surgery, except cholecystectomy and appendectomy 3. MRI during the period that the CorTemptm sensor is within the body (e.g. 1 day preceding the 7-hills run, the day of the 7-hills run and 2 days after the 7-hills run) 4. subject having a cardiac pacemaker or other implanted electromedical device.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The following measurements and assessments will be done: 1) core body temperatue during 24 hrs (telemetry pill) 2) skin temperature (above and below the level of lesion) 3) activity monitoring (sensewear) 4) venous blood withdrawal (before and after exercise for assessment of lactate and plasma sodium concentrations) 5) heart frequency | — |
Secondary
| Measure | Time frame |
|---|---|
| n.a. | — |
Countries
Netherlands
Outcome results
None listed