Habituation or sensitization effects of repetitive nociceptive stimuli measured with cortical event related potentials in patients with and without chronic pain after a lumpectomy or mastectomy and an axillary lymph node dissection.

Habituation or sensitization effects of repetitive nociceptive stimuli measured with cortical event related potentials in patients with and without chronic pain after a lumpectomy or mastectomy and an axillary lymph node dissection. - Cortical plasticity

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON32895

Enrollment

Registered

2009-12-28

Start date

2010-01-01

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronische pijn Generalized hyperalgesia

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients after lumpectomy or mastecomy and an axillary lymph node dissection; 1 to 3 years post OK Patients with pain presented longer than 3 months, will be included in de chronic pain group Aged 18 - 65 years Women

Exclusion criteria

Exclusion criteria: Actual presence of (breast)cancer or metastases. Presence or history of neurological (other than chronic pain) or major psychiatric diseases. Regular intake of medication affecting potentially brain function or EEG signal.

Design outcomes

Primary

Measure	Time frame
N1-P2 peak-to-peak and P300 amplitudes in the event related potentials (EEG).	—

Secondary

Measure	Time frame
1. The quantification of DNIC response 2. The quantification of the subjective intensity of pain 3. The quantification of the nature of pain 4. Baseline parameters: date of birth, date of surgery, treatment technique, medication intake, duration of pain suffering, medical co-morbidity (neurological diseases, psychiatric diseases or diabetes).	—

Countries

Netherlands

Outcome results