lung cancer non-small cell lung cancer
Conditions
Interventions
Insertion of a balloon catheter into the left or right pulmonary artery after
venous puncture in the groin. After insertion, the drug is infused
depending
on the group, a balloon will be inflated after infusion during 10, 20 or 30
minutes
after infusion and/or balloon inflation, the catheter will be removed
immediately.
Sponsors
cardioth chir
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Stage c3a en c3b NSCLC
Exclusion criteria
Exclusion criteria: Other stages of NSCLC, age under 18 years old (however, NSCLC has never been described during childhood), patients who are mentally not able to chose whether to be involved in the study or not, pregnancy or lactation, severe comorbidity, uncontrollable infectious disease, Liver/kidney insufficiency; serum creatinine more than 130 µmol/l and urine creatinine clearance less than 60 ml/min, ALAT and ASAT more than 3 times normal
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary endpoint: toxicity (CTC criteria) | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary endpoint: radiologic response, downstaging, radical resection | — |
Countries
Netherlands
Outcome results
None listed