Ten years of statin therapy started in childhood: efficacy, safety, compliance and tolerability in patients with familial hypercholesterolemia (AfterTen-study)

Ten years of statin therapy started in childhood: efficacy, safety, compliance and tolerability in patients with familial hypercholesterolemia (AfterTen-study) - AfterTen

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON32864

Enrollment

294

Registered

2008-12-12

Start date

2009-01-01

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

familial elevated cholesterol familial hypercholesterolemia

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Those who participated in the LIPIDS trial and their non-affected brothers or sisters

Exclusion criteria

Exclusion criteria: None

Design outcomes

Primary

Measure	Time frame
The main endpoint will be the difference in IMT between FH patients and their non-affected siblings after 10 years follow-up.	—

Secondary

Measure	Time frame
Furthermore, we will investigate change in IMT after 10 years follow-up for various treatment durations and intensities. The occurrence of adverse events and growth and sexual development will be described and compared to healthy siblings. We will also investigate psychological effects.	—

Countries

Netherlands

Outcome results