ataxia spinocerebellar ataxia
Conditions
Interventions
None listed
Sponsors
Erasmus MC, Universitair Medisch Centrum Rotterdam
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: diagnosis of autosomal dominant spinocerebellar ataxia (ADCA) or idiopatic late onset cerebellar ataxia (ILOCA), age of 18 years and beyond, able to interpretate self-assessment scales, signed informed consent
Exclusion criteria
Exclusion criteria: ataxia of unknown origin or other diagnosis age below 18 years severe psychiatric or cognitive deterioration or other conditions that prevent patients from adequate interpretation of self assessment scales
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary study parameters are: difference in FSS-score in our study population compared to (published) FSS scores in healthy controls and furthermore the correlation of FSS score and disease duration, severity of ataxia (quantified with the SARA: scale for assessment and rating of ataxia) and depression (quantified in the Beck depression inventory). , | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary study parameters are: independent correlates of fatigue, studying the association of frequency and severity of fatigue, measured by FSS, and quality of life, motor function, disorders of sleep and cognitive functioning, assessed by the SF-36, the Rotterdam handicap scale, the Pittsburg sleep quality index, the Epworth sleepiness scale(ESS) and the mini mental state examination (MMSE) | — |
Countries
Netherlands
Outcome results
None listed