The significance of intraepithelial lymfocytosis without villous atrophy for the diagnosis of celiac disease.

The significance of intraepithelial lymfocytosis without villous atrophy for the diagnosis of celiac disease. - Marsh 1 study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON32813

Enrollment

Registered

2008-11-27

Start date

2008-12-01

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

celiac disease sprue

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1. Idiopathic intraepithelial lymfocytosis without villus atrophy (Marsh 1) 2. Accountable 3. Above 18 years of age 4. Written informed consent

Exclusion criteria

Exclusion criteria: 1. Proven celiac disease, Crohn's disease, infection with Helicobacter pylori or Giardia lamblia, small bowel vascular disease 2. Non-accountable 3. Under 18 years of age 4. No written informed consent

Design outcomes

Primary

Measure	Time frame
Primary outcome is the prevalence of HLA DQ2 or DQ8.	—

Secondary

Measure	Time frame
Secundary outcome is the prevalence of anti-endomysium antibodies and anti-tissue transglutaminase antibodies. Quality of life.	—

Countries

Netherlands

Outcome results