Betacell and endothelial function in subjects with EXT-1 or EXT-2 mutations

Betacell and endothelial function in subjects with EXT-1 or EXT-2 mutations - BEEM

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON32811

Enrollment

Registered

2008-10-21

Start date

2008-10-01

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cardiovascular disease glucose intolerance

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: >18 years of age Genotype shows EXT-1 or EXT-2 mutation

Exclusion criteria

Exclusion criteria: malignancy with decreased life expectancy diabetes

Design outcomes

Primary

Measure	Time frame
Glycocalyx dimension through SDF imaging	—

Secondary

Measure	Time frame
Plasma glucose/ insulin levels Endothelial function Glycocalyx degradation products Urinary albumin secretion	—

Countries

Netherlands

Outcome results