Iron and malaria: the central role of hepcidin and macrophage function

Iron and malaria: the central role of hepcidin and macrophage function - iron and malaria

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON32793

Enrollment

Registered

2009-09-09

Start date

2010-01-01

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

malaria Plasmodium falciparum infectie

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: healthy, above 18 years

Exclusion criteria

Exclusion criteria: use of iron supplementations (current or in previous 2 years) vegan or vegetarian diet

Design outcomes

Primary

Measure	Time frame
- the change in mRNA expression of hepcidin and other iron regulating proteins of the monocyte after incubation with several stimuli -the change in mRNA expression and protein of cytokines in monocytes after incubation with several stimuli -the change in monocyte iron content	—

Secondary

Measure	Time frame
n.a.	—

Countries

Netherlands

Outcome results