Clinical study of the effect of PEEP ventilation on right ventricular afterload in pediatric patients after cardiac surgery.

Clinical study of the effect of PEEP ventilation on right ventricular afterload in pediatric patients after cardiac surgery. - PEEP and right ventricular afterload

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON32788

Enrollment

Registered

2008-11-18

Start date

2008-12-01

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cardiac performance Mechanical ventilation

Interventions

All patients will be ventilated For 30 minutes without PEEP, for 30 minutes with 8 PEEP and with recruitment and PEEP for 30 minutes. After each ventilation strategy CI will be measured and bloodgas

Eligibility

Age

2 Years to 11 Years

Inclusion criteria

Inclusion criteria: Children weighing > 5 kg and older than 3 months of age Cardiac surgery on CPB

Exclusion criteria

Exclusion criteria: Residual intracardiac shunting (evaluated by TEE after CPB) Hemodynamically instable patients. Rhythm other than sinus Tricuspid regurgitation No informed consent

Design outcomes

Primary

Measure	Time frame
Thermodilution Cardiac Index measurement with PiCCO (PiCCO system; Pulsion Medical Systems, Munich, Germany), right ventricular outflow impedance (TEE), functional residual capacity (GE Healthcare Engstrom Carestation) and arterial blood gases will be measured.	—

Secondary

Measure	Time frame
- Heart rate- Systemic arterial blood pressure- Central venous pressure - Atrial pressure	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)