niet van toepassing
Conditions
Interventions
Transcranial direct current stimulation (tDCS) will be delivered by a
battery-driven constant DC current stimulator (Eldith DC Stimulator (CE 0118),
Ilmenau) using a pair of electrodes in a 5-7 cm (
Sponsors
Universiteit Utrecht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Non-smoking, right-handed, 18-35 years
Exclusion criteria
Exclusion criteria: Skin disease, metal in cranium, use of psychotropic drugs, including cannabis, XTC, amphetamines and cocaine, epilepsy or family history of epilepsy, history of closed-head injury, history of neurological or psychiatric disorders, medication use (i.e., benzodiazepines, antidepressants and neuroleptica), cardiac pacemaker, pregancy, of electronic hearing devices.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Cerebral physiology: Transcranial magnetic stimulation (TMS) will be used to examine brain asymmetry by measuring cortical excitability of the left and right hemisphere, and left-to-right and right-to-left inter-hemispheric connectivity (see also Protocol 07-044/O) (page 5-7 of the protocol). 2. Background electroencephalogram: To monitor changes in electric activity an background electroencephalogram (EEG) will be recorded from 32 scalp locations according to the International 10-20 EEG System using Ag*AgCl-tipped electrodes (sampling rate: 256 Hz) before and immediately after tDCS (page 7-8 of the protocol). 3. Mood will be monitored using the 20-item Profile of Mood States questionnaire (Shacham, 1983) (duration: 10 min). Selective attention for emotional faces will be indexed using an emotional Stroop task comparing colour-naming latencies for neutral, angry, fearful and happy faces (page 8 of the protocol). | — |
Secondary
| Measure | Time frame |
|---|---|
| not applicable. | — |
Countries
Netherlands
Outcome results
None listed