Psychopathy sociopathy
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Sint Radboud
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: • Age 18-55 years. • Men. • Group 1: Patient, meeting the DSM-IV criteria for ASPD and scoring * 26 on the PCL-R. • Group 2: Patient, meeting the DSM-IV criteria for ASPD; and showing low levels of psychopathy (PCL-R
Exclusion criteria
Exclusion criteria: General exclusion criteria for fMRI: Metal implants or splinters, surgical clips, protheses, artificial heart valves, claustrophobia, electronic equipment in body (such as a pacemaker), pregnancy, epilepsy. ;Psychiatric: • Recurrent Major Depressive disorder or Single Major Depressive disorder within five years. • Bipolar disorder • Schizophrenia, delusional disorder, schizoaffective disorder, schizopheniform disorder or other psychotic disorders • Schizoid or schizotypical personality disorder • (Current) alcohol- or substance intoxication • Anti-social personality disorder/Psychopathy co-morbidity in healthy volunteers • ADHD • First degree relatives with DSM IV axis I schizophrenia, or schizophreniform disorder • Mental retardation;Somatic • Visual and auditory disorders • Neurological disorders • First degree relatives with any relevant neurological disorders;Pre-testing use of drugs and substances • Use of alcohol within 24 hours before measurement. • Use of cannabis or other illicit drugs within the week before measurement. • Use of any psychotropic medication, other than benzodiazepines, during the 5 days before measurement. • Use of benzodiazepines within 3 times T¬1/2 before measurement. • Smoking within 3 hours before measurement.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| During the performance of the tasks we will collect behavioural, psychophysiological (heart rate and eye tracking) data and functional imaging data. | — |
Secondary
| Measure | Time frame |
|---|---|
| - | — |
Countries
Netherlands
Outcome results
None listed