Influence of Variations in Systemic Blood Flow and Blood Pressure on Cerebral Oxygenation during Cardiac Surgery.

Influence of Variations in Systemic Blood Flow and Blood Pressure on Cerebral Oxygenation during Cardiac Surgery. - Influence of Blood Flow and Blood Pressure on Cerebral Oxygenation

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON32638

Enrollment

Registered

2010-02-16

Start date

2009-12-01

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mensen aan een extra-corporeel circuit The influence of variations in blood pressure and variations in blood flow on cerebral autoregulation

Interventions

When the patient is on cardiopulmonary bypass, we will modify the systemic blood pressure and/or systemic blood flow while measuring the cerebral oxygenation. We have one series of measurements duri

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: -patient is older than 18 years -patient is scheduled to undergo elective cardiac surgery with the use of an cardiopulmonary bypass. -informed consent

Exclusion criteria

Exclusion criteria: -patient under 18 years old -patient older than 70 years -Carotid artery stenosis (examination before surgery with echo-Dopplergraphy) -emergency operations -severe COPD -no informed consent -SaO2

Design outcomes

Primary

Measure	Time frame
The relationship between variations in blood pressure and blood flow on the one hand, and cerebral oxygenation on the other hand.	—

Secondary

Measure	Time frame
The effect of phenylephrin and vasopressin on cerebral oxygenation	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)