Oxytocin and brain responses to infant crying

Oxytocin and brain responses to infant crying - Oxytocin and brain responses to infant crying

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON32632

Enrollment

Registered

2008-11-03

Start date

2009-11-22

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

child abuse/neglect child acuse emotional neglect

Interventions

The subjects will take 6 puffs of nasal spray containing 4 IU/ puff of oxytocin (Syntocinon, Novartis), or 6 puffs of a placebo-spray (NaCl solution).

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: female 21-55 years old

Exclusion criteria

Exclusion criteria: contra-indications for fMRI (which include metal implants, heart arrhythmia, claustrophobia, and possible pregnancy) head trauma drug or alcohol abuse psychiatric disorder nasal disease or obstruction smoking breast feeding oral contraceptive use.

Design outcomes

Primary

Measure	Time frame
Task-FMRI: signal change in emotion (regulation) regions during brain activation. Resting state FMRI: functional connectivity strength between brain regions at rest.	—

Secondary

Measure	Time frame
NVT	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)