Feasibility of fibered confocal fluorescence microscopy (FCFM) in patients with pulmonary diseases.

Feasibility of fibered confocal fluorescence microscopy (FCFM) in patients with pulmonary diseases. - FCFM in patients with pulmonary diseases.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON32614

Enrollment

Registered

2009-01-14

Start date

2008-12-01

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pulmonary diseases

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Adult patients (18-75 yr) with the following pulmonary diseases will be studied: 1. three patients with a peripheral lung tumor who undergo bronchoscopy as part of the routine assessment 2. three patients with a previous diagnosis or clinical suspicion of sarcoidosis. 3. three patients with COPD (GOLD II-IV) (smokers or ex-smokers, postbronchodilator (after inhalation of 400 mcg salbutamol) FEV1/FVC 12% after inhalation of 400 mcg salbutamol)

Exclusion criteria

Exclusion criteria: Patients who are > 80 years of age or who have previously undergone radiotherapy will be excluded.

Design outcomes

Primary

Measure	Time frame
The microscopic autofluorescence structure of normal and pathologic bronchial mucosae will be analysed. Pathology specimens will analyzed by a pathologists with expertise in pulmonary disorders. Characteristics of images will be defined, and related to the pathological findings.	—

Countries

Netherlands

Outcome results