inadequaat herstel (overreaching) overreaching
Conditions
Interventions
All subjects will receive the following study procedures: a repeated two bout
VO2max tests with cognitive tests and exhaled breath and blood pressure
measurements. Subjects will not sleep during one
Sponsors
TNO
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - male - 18-35 years of age at the start of the experiment - well trained (at least training 2 times a week and participation in competative sports) - non smoker (or stopped at least 2 years ago) - familiar with VO2-max tests
Exclusion criteria
Exclusion criteria: 1 Participation in any clinical trial including blood sampling and/or administration of substances up to 30 days before Day 01 of this study 2 Having a history of medical or surgical events that may significantly affect the study. 3 Prescribed medication that may interfere with the study outcome 4 Alcohol consumption >28 units/week 5 Not having a general practitioner 6 Not willing to accept information-transfer concerning participation in the study, or information regarding his/her health, findings at anamnesis or physical examination and eventual adverse events to and from his general practition
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected that sleep deprivation combined with strenuous exercise will increase the difference between the first and second bouts of cognitive and physical tests, which will result in differences in hormone level, oxidative stress and activity of the autonomic nervous system. | — |
Secondary
| Measure | Time frame |
|---|---|
| Oxidative stress parameters and immune function are followed in time to evaluate use of these as indicators for recovery. They will be compared with the results of differences in hormone levels and autonomic nervous system. | — |
Countries
Netherlands
Outcome results
None listed