PRedicting Aseptic Loosening through InnatE immunity

PRedicting Aseptic Loosening through InnatE immunity - PRALINE

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON32587

Enrollment

100

Registered

2010-01-28

Start date

2010-03-01

Completion date

Unknown

Last updated

2025-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

knieprothese knee prosthesis knee replacement arthroplasty

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Patients over 18 years, who underwent elective knee replacement arthroplasty. - Patients who are part of an RSA-cohort and whose MTPM at 1 year have been measured.

Exclusion criteria

Exclusion criteria: - No measurable MTPM at 1 year, or inadequate registration. - Tibia component in frontal plane greater than 5 ° varus or valgus 5.

Design outcomes

Primary

Measure	Time frame
Maximum Total Point Motion at 1 year, measured by RSA. PAM3Cys and LPS-stimulated cytokine profiles.	—

Secondary

Measure	Time frame
NA.	—

Countries

Netherlands

Outcome results