CADASIL
Conditions
Interventions
None listed
Sponsors
Leids Universitair Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Confirmed NOTCH3 mutation Age: 18 years or older Mental competency
Exclusion criteria
Exclusion criteria: MRI contraindications
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| - Average thickness of the specific cortical layers, compared to those of the control subjects - Focal abnormalities in the specific cortical layers - Average wall thickness of the medial meningeal artery and the relation with patient age, compared to control subjects - Shape of SLLs and relation with blood vessels - Number of microbleeds and age distribution | — |
Countries
Netherlands
Outcome results
None listed