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CADASIL MRI on 7 Tesla 'a cortical exploration journey'

CADASIL MRI on 7 Tesla 'a cortical exploration journey' - CADASIL MRI on 7 Tesla

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON32570
Enrollment
35
Registered
2008-12-24
Start date
2009-03-17
Completion date
Unknown
Last updated
2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

CADASIL

Interventions

None listed

Sponsors

Leids Universitair Medisch Centrum
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Confirmed NOTCH3 mutation Age: 18 years or older Mental competency

Exclusion criteria

Exclusion criteria: MRI contraindications

Design outcomes

Primary

MeasureTime frame
- Average thickness of the specific cortical layers, compared to those of the control subjects - Focal abnormalities in the specific cortical layers - Average wall thickness of the medial meningeal artery and the relation with patient age, compared to control subjects - Shape of SLLs and relation with blood vessels - Number of microbleeds and age distribution

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)