Positron Emission Tomography for detection of histologic transformation of indolent non-Hodgkin*s lymphoma: a pilot study

Positron Emission Tomography for detection of histologic transformation of indolent non-Hodgkin*s lymphoma: a pilot study - PET scan and histologic transformation of indolent NHL

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON32557

Enrollment

Registered

2008-09-24

Start date

2008-11-27

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

follicular lymphoma low grade lymphoma

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria 1. Patients with newly diagnosed follicular lymphoma or newly diagnosed histological transformation of follicular lymphoma proven by histological examination. 2. Ann Arbor stage at diagnosis: II, III or IV. 3. at least one lesion > 2 cm diameter 4. After the diagnosis and before performing both PET scans they have not received any treatment. 5. Ability to remain supine for 60 min. (PET) 6. Written informed consent.

Exclusion criteria

Exclusion criteria: Exclusion criteria 1. Uncontrolled diabetes mellitus. 2. Physical inability to access PET facilities.

Design outcomes

Primary

Measure	Time frame
1. detection rate (number of true positive PET lesions for either tracer, using CT as reference test) 2. relative tracer uptake (SUV) for either tracer (lesion by lesion analysis, lesion with highest uptake of FDG or FLT) 3. lowest and highest SUV for either tracer within one patient.	—

Secondary

Measure	Time frame
not applicable.	—

Countries

Netherlands

Outcome results