Study To Investigate Carotid atherosclerosis in carriers of LCAT gene mutations and unaffected family controls: A 3.0 Tesla Magnetic Resonance Imaging study

Study To Investigate Carotid atherosclerosis in carriers of LCAT gene mutations and unaffected family controls: A 3.0 Tesla Magnetic Resonance Imaging study - STIC-LCAT

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON32476

Enrollment

Registered

2008-09-10

Start date

2008-09-01

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

atherosclerosis cardiovascular disease

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Subjects who are carriers of LCAT gene mutations, aged between 18 and 75 years of age, and healthy unaffected family controls, aged between 18 and 75 years, matched for age, gender, body mass index (BMI, in kg/m2) and smoking.

Exclusion criteria

Exclusion criteria: Metal in the body, as a result of e.g. osteosynthetic material, pacemaker or artificial cardiac valves; claustrophobia; surgery performed in the area of measurement (Carotid artery region); cardiac arrhythmias.

Design outcomes

Primary

Measure	Time frame
mean wall area of carotid arteries as assessed by MRI	—

Secondary

Measure	Time frame
-	—

Countries

Netherlands

Outcome results