Anxiety disorders Depression
Conditions
Interventions
None listed
Sponsors
Radboud Universiteit Nijmegen
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - Gender: male and female - Age: >18 years - Patients undergoing ECT for unipolar major depressive disorder with and without psychotic features. - Patients are medication free or under a stable therapy with antidepressants - Normal or corrected-to-normal vision - Normal or corrected-to-normal hearing - Willingness and ability to give written informed consent and willingness and ability to understand the nature and content, to participate and to comply with the study requirements.
Exclusion criteria
Exclusion criteria: - Age:
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| - Emotional memory: Difference in memory for emotional vs neutral material. - General effect of ECT: Difference in general memory pre- and post-ECT. | — |
Primary
| Measure | Time frame |
|---|---|
| - Reactivation: Difference in memory for reactivated vs non-reactivated material. - Sustained memory disruption: Difference in memory for reactivated vs non reactivated material after a delay period controlling for spontaneous recovery. - Time-dependency: Difference in memory for reactivated vs non-reactivated material immediately after ECT and 24h after ECT. - Secondary encoding: Difference in reactivated memory vs non-reactivated memory post- and pre-ECT | — |
Countries
Netherlands
Outcome results
None listed