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thrombogenicity and platelet reactivity as risk factors for postoperative microemboli signals in patients undergoing carotid endarterectomy

thrombogenicity and platelet reactivity as risk factors for postoperative microemboli signals in patients undergoing carotid endarterectomy - MES (Micro Embolism Signal)

Status
Unknown
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON32409
Enrollment
100
Registered
2008-12-15
Start date
Unknown
Completion date
Unknown
Last updated
2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

arteriosclerosis stroke

Interventions

None listed

Sponsors

Academisch Ziekenhuis Maastricht
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: patients with an ischemic stroke or TIA (first episode or recurrent disease) AND: an ipislateral stenosis of the carotid artery for which operation of the carotid artery is indicated. Patients need to have an adequate transtemporal window for TCD monitoring og the ateria cerebri media Age > 18 year and

Exclusion criteria

Exclusion criteria: proven coagulopathies pregnancy active infections chronic inflammatory diseases anti-phospholipid syndrome active malignancy recent cardiovascular intervention (

Design outcomes

Primary

MeasureTime frame
The amount (mean and peak) of MES, measurd with TCD, starting from the first postoperative hour, during a period of 3 hours.—

Secondary

MeasureTime frame
a recurrent ipsilateral ischaemic stroke, or death within a period of 1 year starting from the day of the operation—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)