Skip to content

Neuronal communication in Autism Spectrum Disorders: synchrony and coherence in the motor system

Neuronal communication in Autism Spectrum Disorders: synchrony and coherence in the motor system - Neuronal communication in Autism Spectrum Disorders

Status
Unknown
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON32406
Enrollment
60
Registered
2008-05-20
Start date
2008-01-01
Completion date
Unknown
Last updated
2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

autism Pervasive developmental disorder

Interventions

None listed

Sponsors

Universitair Medisch Centrum Sint Radboud
Lead Sponsor

Eligibility

Age
2 Years to 17 Years

Inclusion criteria

Inclusion criteria: (1) To be included in the Autism Spectrum Disorders- group the participant should meet criteria for Autistic disorder or Asperger Disorder as specified in the DSM-IV. To be included in the ADHD-group the participant should meet criteria for ADHD as specified in the DSM-IV. (2) Age between 8 and 18 years old.

Exclusion criteria

Exclusion criteria: ASD-group: Co-morbid neuropsychiatric disorders like ADHD, tic-disorders and epilepsy. ADHD-group: Co-morbid neuropsychiatric disorders like ASD, tic-disorders and epilepsy. Typically developed group: neuropsychiatric disorders like ASD, ADHD, tic-disorders and epilepsy.

Design outcomes

Primary

MeasureTime frame
(1) Time-frequency analyses will be applied to calculate MEG power in a given frequency band (beta), over a given timeinterval for a given group of sensors. Mean beta-power will be calculated for each group and compared between groups. (2) Coherence between MEG signals recorded over motorcortex and EMG signals recorded at the right first dorsal interosseus (FDI) muscle will be calculated. Mean coherence for a given time and frequency interval will be calculated for each group and comparisons will be made.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)