labor pain
Conditions
Interventions
Remifentanil group: 40microgram boluses, lockout time 2 min. Maximum dose
limit is 1200 microgram/hour.
Epidural group: ropivacaine plus sufentanil.
Loading dose 25 mg (12.5 ml ropivacaine 0.2%), fo
Sponsors
Leids Universitair Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: * Age *18 years * Between 37-42 weeks of gestation * Singleton pregnancy * ASA physical status I or II
Exclusion criteria
Exclusion criteria: * Prior administration of regional of opioid analgesia (during this delivery). * Morbid obesity (BMI * 40 kg/m2) * Drug allergy: history of hypersensitivity to opioid or local anesthetic substances * High risk pregnancy: including severe asthma (daily use of medication), insulin dependent diabetes, severe pre-eclampsia (proteinuria * 5 grams) * Use of antibiotics during delivery * Initial maternal SpO2 of less than 98% * Initial maternal temperature of 38°C or higher. * Cervical dilation of > 7 cm * Ruptured membranes for more than 24 hours at time of inclusion * Contraindication for epidural analgesia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| * Maternal temperature * Maternal saturation | — |
Secondary
| Measure | Time frame |
|---|---|
| * To compare the incidences of other known side effects, in particular nausea, pruritus, sedation and hypotension. * Fetal outcome as determined by Apgar scores, umbilical cord pH, NACS and requirement for naloxone. | — |
Countries
Netherlands
Outcome results
None listed