Encircling Cryoablation of Ventricular Arrhythmia Concomitant with Left Ventricular Reconstruction. A Comparison of the Effectivity of Combined Endo and Epicardial Cryoablation versus Endocardial Cryoablation alone.

Encircling Cryoablation of Ventricular Arrhythmia Concomitant with Left Ventricular Reconstruction. A Comparison of the Effectivity of Combined Endo and Epicardial Cryoablation versus Endocardial Cryoablation alone. - Cryoablation of Ventricular Arrhythmia concomitant with LV Reconstruction

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON32246

Enrollment

Registered

2008-05-13

Start date

2008-11-05

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ventricular Arrhythmia

Interventions

40 patients are randomized to either both endocardial and epicardial cryoablation of borderzone of myocardial scar or endocardial cryoablation alone.

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Acceptation for surgical left ventricular reconstruction according to Dor Spontaneous or inducible ventricular arrhythmia

Exclusion criteria

Exclusion criteria: Age

Design outcomes

Primary

Measure	Time frame
This study will test the hypothesis that the combined endo- and epicardial ablation therapy but not the endocardial ablation will result in isolation of the VA substrate and that the combined approach will be more effective in preventing reinducibility and spontaneous occurrence of VA. The main study parameters are acute conduction properties across the ablation line intraoperatively. inducibility of VTs before and after surgery and spontaneous VA as registered by the internal cardiac defibrillator.	—

Measure

Time frame

This study will test the hypothesis that the combined endo- and epicardial ablation therapy but not the endocardial ablation will result in isolation of the VA substrate and that the combined approach will be more effective in preventing reinducibility and spontaneous occurrence of VA. The main study parameters are acute conduction properties across the ablation line intraoperatively. inducibility of VTs before and after surgery and spontaneous VA as registered by the internal cardiac defibrillator.

—

Secondary

Measure	Time frame
Secundary study parameters include inducibility of VTs before and after surgery and spontaneous VA as registered by the internal cardiac defibrillator.	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)