HITEA: "Health Effects of Indoor Pollutants: Integrating microbial, toxicological and epidemiological approaches"

HITEA: "Health Effects of Indoor Pollutants: Integrating microbial, toxicological and epidemiological approaches" - HITEA: Indoor air quality in primary schools and health

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON32234

Enrollment

1560

Registered

2009-02-17

Start date

2009-03-02

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

respiratory tract inflammation and obstruction

Interventions

None listed

Eligibility

Age

2 Years to 99 Years

Inclusion criteria

Inclusion criteria: primary school children from group 3-8 and their teachers. For the longitudinal part: primary school children from group 3-7 with symptoms highly suggestive of asthma and teachers.

Exclusion criteria

Exclusion criteria: Primary school children from group 1 and 2

Design outcomes

Primary

Measure	Time frame
- To characterize the microbial, immunological, toxicological, and dampness-related properties of indoor air in school buildings in the Netherlands; - to study the relation between the different obtained exposure measurements in schools: ventilation, CO2 and allergens levels, moisture and microbial components; - to study the prevalence of respiratory symptoms and specific sensitization to environmental allergens in school children; - to reveal the health effects associated with indoor air exposures in school children and teachers; - to study the mechanisms underlying the health effects; In addition we want to evaluate the effect of swimming pool attendance on respiratory health of school children. Therefore, we will study: - the effect of swimming pool attendance and exposure to trichloramine in swimming pool air on self reported respiratory health symptoms and lung function measurements; - the influence of swimming pool attendance and exposure to chloramine in swimming pool air on surfactant associated proteins A and B (SP-A and SP-B) and 16 kDA Clara cell protein 16 (CC16) levels in blood of school children; - the relationship between surfactant associated proteins A and B (SP-A and SP-B) and 16 kDA Clara cell protein 16 (CC16) levels in blood and respiratory health symptoms and lung function.	—

Measure

Time frame

- To characterize the microbial, immunological, toxicological, and dampness-related properties of indoor air in school buildings in the Netherlands; - to study the relation between the different obtained exposure measurements in schools: ventilation, CO2 and allergens levels, moisture and microbial components; - to study the prevalence of respiratory symptoms and specific sensitization to environmental allergens in school children; - to reveal the health effects associated with indoor air exposures in school children and teachers; - to study the mechanisms underlying the health effects; In addition we want to evaluate the effect of swimming pool attendance on respiratory health of school children. Therefore, we will study: - the effect of swimming pool attendance and exposure to trichloramine in swimming pool air on self reported respiratory health symptoms and lung function measurements; - the influence of swimming pool attendance and exposure to chloramine in swimming pool air on surfactant associated proteins A and B (SP-A and SP-B) and 16 kDA Clara cell protein 16 (CC16) levels in blood of school children; - the relationship between surfactant associated proteins A and B (SP-A and SP-B) and 16 kDA Clara cell protein 16 (CC16) levels in blood and respiratory health symptoms and lung function.

—

Secondary

Measure	Time frame
-	—

Countries

Netherlands

Outcome results