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A study investigating the possible relation between inter-subject variation in parameters of whole saliva, pellicle and differences in susceptibility to erosion

A study investigating the possible relation between inter-subject variation in parameters of whole saliva, pellicle and differences in susceptibility to erosion - The relation between dental erosion and saliva/pellicle characteristics

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON32183
Enrollment
50
Registered
2008-12-15
Start date
2008-06-01
Completion date
Unknown
Last updated
2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

tandweefsel dental erosion wear

Interventions

None listed

Sponsors

Universitair Medisch Centrum Groningen
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Adults with an ASA score of 1 with a rehabilited dentition

Exclusion criteria

Exclusion criteria: An ASA score of 2 or higher, severe periodontal disease (Dutch periodontal screening index, DPSI > 2) and an unrehabilitated dentition

Design outcomes

Primary

MeasureTime frame
From all participants the saliva total protein concentration will be determined. Also the loss of hydroxyapatite after an erosive challenge will be measured. The correlation between the total protein concentration of saliva and the susceptibility to erosive wear will be calculated.

Secondary

MeasureTime frame
From all participants the saliva composition (proteins and minerals), saliva characteristics (pH, buffer capacity, viscosity) and pellicle composition (proteins) will be determined. The correlation between different saliva parameters and the susceptibility to erosive wear will be calculated.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)