oesophageal cancer oesophageal neoplasm
Conditions
Interventions
None listed
Sponsors
Nederlands Kanker Instituut
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1) Patients presenting at the NKI-AvL or LUMC for the treatment of oesophageal cancer. 2) Planned gastroduodenoscopy (for diagnosis, feeding tube insertion, dilatation, etc.) or endoscopic ultrasonography (for staging). 3) No evidence of distant metastases at presentation (by endoscopic ultrasonography, computer tomography, and positron emission tomography) 4) Able and willing to undergo tissue sampling for tumour genetic analyses. 5) Age > 18 years.
Exclusion criteria
Exclusion criteria: 1) Any condition that prohibits safe biopsy sampling (e.g. use of anticoagulants). 2) Incapacity or unwillingness to give written informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The following comparisons will be performed: 1) Patients who are diagnosed with metastatic disease within 1 year after diagnosis versus patients without metastatic disease within 1 year after diagnosis. 2) Patients in whom the tumour shows response to preoperative or definitive(chemo)radiotherapy versus patients in whom the tumour is unresponsive to this type of treatment. | — |
Countries
Netherlands
Outcome results
None listed