Recurrent/persistent primary hyperparathyroidism, clinical, pathological and genetic aspects

Recurrent/persistent primary hyperparathyroidism, clinical, pathological and genetic aspects - Recurrent/persistent primary hyperparathyroidism

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON32114

Enrollment

Registered

2008-12-17

Start date

2008-12-22

Completion date

Unknown

Last updated

2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hyperactive parathyroid glands primary hyperparathyroidism

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: proven recurrent/persistent primary hyperparathyroidism after excision of one or more pathological parathyroid glands

Exclusion criteria

Exclusion criteria: primary hyperparathyroidism due to MEN syndrome, lithium use or parathyroid carcinoma, secundary or tertiary (autonomous) hyperparathyroidism due to long time vitamin D deficiency or chronic renal failure

Design outcomes

Primary

Measure	Time frame
1. Clinical and biochemical parameters 2. Pre-operative localization studies; MiBi-SPECT, PTH sampling 3. Intra-operative PTH measurements 4. Operative data 5. Pathology data 6. DNA analysis on leukocytes, formaline fixed paraffine imbedded (FFPE) tissue or frozen material	—

Secondary

Measure	Time frame
No secondary study parameters	—

Countries

Netherlands

Outcome results