Arterial and venous uptake pharmacokinetics of inhaled sevoflurane

Arterial and venous uptake pharmacokinetics of inhaled sevoflurane - Sevoflurane pharmacokinetics

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON32096

Enrollment

Registered

2008-08-12

Start date

2009-07-01

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Het onderzoek heeft geen betrekking op aandoeningen Techniques in anesthesiology

Interventions

Application of 1% sevoflurane during anesthesia (standard procedure)

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Age 35-70 years Scheduled for elective neurosurgical procedures where an arterial and central venous line will be applied. Expected surgery time > 2 hours Informed consent

Exclusion criteria

Exclusion criteria: Anemia (Hb

Design outcomes

Primary

Measure	Time frame
The primary endpoint consists of evaluation of the pharmacokinetics of arterial and venous uptake of inhaled sevoflurane by gas chromatography.	—

Secondary

Measure	Time frame
The second endpoint is defined as determination of the end-tidal fraction ratio of inhaled sevoflurane over time.	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)