Ciculating endothelial cells in Preeclampsia

Ciculating endothelial cells in Preeclampsia - CEC study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON32080

Enrollment

Registered

2008-03-25

Start date

2008-04-01

Completion date

Unknown

Last updated

2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

preeclampsia

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Case group: - diagnosis of severe preeclampsia based upon the ACOG criteria - written informed consent Control group: - ASA class I pregnant patients visiting our out-patient clinic - written informed consent

Exclusion criteria

Exclusion criteria: Control group: - ASA class II or more - previous pregnancies with placental syndromes as preeclampsia, growth retardation and/or gestational diabetes - placental syndrome during the index pregnancy

Design outcomes

Primary

Measure	Time frame
Primary study parameter: CEC levels in patients with severe preeclampsia	—

Secondary

Measure	Time frame
Secondary study parameters - To analyze the relation of CEC levels with organ damage and dysfunction. - To analyze the relation of CEC levels with clinical parameters as bloodpressure and proteinuria. - Correlation between CEC levels and levels of circulating thrombomodulin and other soluble markers like endoglin and e-selectin.	—

Countries

Netherlands

Outcome results