Rectal Mucosal Perfusion and Oxygenation in Patients with Rectal Cancer; Variables to Predict Response to Radiation Therapy and Anastomotic Leakage?

Rectal Mucosal Perfusion and Oxygenation in Patients with Rectal Cancer; Variables to Predict Response to Radiation Therapy and Anastomotic Leakage? - Rectal Mucosal Perfusion and Oxygenation in Patients with Rectal Cancer

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON32076

Enrollment

Registered

2008-10-29

Start date

2008-03-01

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

rectal cancer rectal carcinoma

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing neoadjuvant radiation therapy at the VU University medical center for rectal cancer. 2. age 18 years and older 3. informed consent

Exclusion criteria

Exclusion criteria: 1. no informed consent 2. palliative treatment

Design outcomes

Primary

Measure	Time frame
-Correlation between perfusion and oxygenation in tumor and rectal mucosa and downgrading of the tumor.	—

Secondary

Measure	Time frame
-Radiation therapy induced changes in the perfusion and oxygenation of the rectal mucosa. -Correlation between rectal mucosal perfusion and oxygenation and anastomotic leakage.	—

Countries

Netherlands

Outcome results