Haemodynamics, arterial stiffness and endothelial function in young prehypertensive subjects

Haemodynamics, arterial stiffness and endothelial function in young prehypertensive subjects - Artertial properties in prehypertension

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON32038

Enrollment

Registered

2008-05-20

Start date

2008-05-01

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

high-normal blood pressure prehypertension

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1. willing and able to participate in the study protocol 2. age 18-30 years 3. average blood pressure 130-139/85-89 mmHg 4. blood pressure healthy controls with optimal blood pressure:

Exclusion criteria

Exclusion criteria: 1. history of cardiovascular disease 2. chronic use of prescribed medication 3. any disease requiring chronic treatment by a medical specialist 4. cardiac arrhythmia

Design outcomes

Primary

Measure	Time frame
The difference between prehypertensive and normotensive subjects in augmentation index	—

Secondary

Measure	Time frame
The difference between prehypertensive and normotensive subjects in: - Pulse wave velocity - Central aortic blood pressure - Systemic vascular resistance (SVR) - Vascular changes (AIx and SVR) after single stimulation with salbutamol and nitroglycerin - Endothelial function as assessed with endopat2000 - Correlation between these parameters	—

Countries

Netherlands

Outcome results