Bowel plus anastomotic perfusion and oxygenation in colorectal surgery: variables to predict anastomotic leakage?

Bowel plus anastomotic perfusion and oxygenation in colorectal surgery: variables to predict anastomotic leakage? - Anastomotic perfusion

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON32021

Enrollment

210

Registered

2008-10-31

Start date

2009-04-29

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

darmperfusie en naadlekkage blood flow bowel perfusion

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1. patients undergoing the following surgery: left or right hemicolectomy, simoid resection, anterior resection or partial small bowel resection with primary anastomosis. 2. age 18 years and older 3. surgery at VU medical center 4. oral and written informed consent

Exclusion criteria

Exclusion criteria: 1. no informed consent 2. palliative surgery 3. emergency surgery

Design outcomes

Primary

Measure	Time frame
Primary study parameters -oxygen saturation of haemoglobin at anastomosis including systemic saturation level. -relative amount of haemoglobin at anastomosis including systemic haemoglobin level. -blood flow at anastomosis site. -blood velocity at anastomosis site. -functional recovery of perfusion and oxygenation at the anastomosis after reperfusion. Primary study outcomes -clinical signs of anastomotic leakage, objectified by abdominal CT scan. -stricture at site of anastomosis	—

Measure

Time frame

Primary study parameters -oxygen saturation of haemoglobin at anastomosis including systemic saturation level. -relative amount of haemoglobin at anastomosis including systemic haemoglobin level. -blood flow at anastomosis site. -blood velocity at anastomosis site. -functional recovery of perfusion and oxygenation at the anastomosis after reperfusion. Primary study outcomes -clinical signs of anastomotic leakage, objectified by abdominal CT scan. -stricture at site of anastomosis

—

Secondary

Measure	Time frame
none applicable	—

Countries

Netherlands

Outcome results