Cortical activation in pre-lingually deaf adults, with and without a cochlear implant

Cortical activation in pre-lingually deaf adults, with and without a cochlear implant - Cortical activation in pre-lingually deaf adults

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON31996

Enrollment

Registered

2008-05-20

Start date

2008-02-11

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sensorineural hearing loss severe hearing loss and deafness

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1. Adults (18 years of age or older) 2. Right handed 3. Normal hearing group: having a pure-tone air conduction thresholds 50% (open-set monosyllable lists according to the *Nederlandse Vereniging van Audiologie* (NVA)). b. Implanted group with poor results: consonant-vowel-consonant (CVC) score 90 dB and

Exclusion criteria

Exclusion criteria: 1.Pregnancy/breastfeeding 2.Diabetis Mellitus (type I and II) 3.Claustrophobic

Design outcomes

Primary

Measure	Time frame
The cerebral glucose metabolism (and hence the cortical activity) is measured by the regional [18F]-FDG uptake ([18F]-FDG is an analogue for glucose). To study the auditory neural processing with ERPs, the amplitude, latency and morphology of the N1, P2 and P300 responses are evaluated.	—

Secondary

Measure	Time frame
not aplicable	—

Countries

Netherlands

Outcome results