platelet activation in lung transplantation

platelet activation in lung transplantation - platelet activation in lung transplantation

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON31994

Enrollment

Registered

2008-12-02

Start date

2008-06-01

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

emphysema lung failure

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Age >= 18 years First bilateral lungtransplantation (study population), planned off-pump. Off-pump coronary artery bypass grafting (control group) Non-inflammatory disease Informed consent

Exclusion criteria

Exclusion criteria: Combined organ transplantations Use of pre-operative antiplatelet medication Peroperative use of CPB Peroperative transfusion of platelet concentrates Inflammatory diseases (e.g. cystic fibrosis)

Design outcomes

Primary

Measure	Time frame
The development of functional properties of primary hemostasis (especially of platelets and vWF) during lung transplantation. The appearance of (partly) activated circulating platelets during lung transplantation, especially after reperfusion of the graft.	—

Secondary

Measure	Time frame
none	—

Countries

Netherlands

Outcome results