Identification of predictive parameters for typhlitis in AML patients treated with intensive chemotherapy

Identification of predictive parameters for typhlitis in AML patients treated with intensive chemotherapy - Typhlitis in AML

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON31938

Enrollment

Registered

2008-12-05

Start date

2010-06-01

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

AML

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - age 18-70 years - patients with AML treated with intensive chemotherapy

Exclusion criteria

Exclusion criteria: Ineligible to perform the proposed tests.

Design outcomes

Primary

Measure	Time frame
- Defining the severity of epithelial dysfunction measured with mucositis score; the stool volume; the calprotectin level in the stool the urinary Cr EDTA excretion and serum IL-8 and CRP levels. - Typhlitis based on clinical symptomatology and CT-scanning abdomen. - DNA isolation from normal peripheral blood cells for determining polymorphism of metabolism genes.	—

Secondary

Measure	Time frame
Not applicable.	—

Countries

Netherlands

Outcome results