The Effect of Inflammation on Bone Cells

The Effect of Inflammation on Bone Cells - The Effect of Inflammation on Bone Cells

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON31917

Enrollment

Registered

2008-07-08

Start date

2008-07-22

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

inflammatory bowel disease

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1. Men and women between the age of 18 and 50 years 2. Informed consent 3a. Patients suffering from Crohn*s disease of at least 3 months duration, confirmed by radiography, endoscopy and histology (according to the Lennard-Jones criteria ; Lennard-Jones 1989). 3b. Patients suffering from Ulcerative Colitis of at least 3 months duration, confirmed by radiography, endoscopy and histology (according to the Lennard-Jones criteria) 4. a BMI between 18-30

Exclusion criteria

Exclusion criteria: 1. Co-morbidity influencing bone metabolism - Renal insufficiency (creatinin clearance

Design outcomes

Primary

Measure	Time frame
osteoblast proliferation, osteoblast differentiation, osteoclastogenesis, osteoclast function and bone histomorphometry	—

Countries

Netherlands

Outcome results