Do the effects of orenatal famine exposure pass down generations? An epigenitic study.

Do the effects of orenatal famine exposure pass down generations? An epigenitic study. - Transgenerational effects of the Dutch Famine. An epigenetic study.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON31890

Enrollment

2580

Registered

2008-07-01

Start date

2008-08-01

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cardiovascular disease

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Men and women born at the time of the Dutch Famine 1944-1945 in the Wilhelmina Gasthuis in Amsterdam, their mothers(F0) and children(F2).

Exclusion criteria

Exclusion criteria: NVT

Design outcomes

Primary

Measure	Time frame
Primary outcome: % methylation of the CpG regions of 4 candidategenes.	—

Secondary

Measure	Time frame
Secondary outcome: health of F2.	—

Countries

Netherlands

Outcome results