Effect of droperidol 2,5 mg added to 100 mg morfine in PCA therapy in combination with ondansetron and dexamethasone against PONV.

Effect of droperidol 2,5 mg added to 100 mg morfine in PCA therapy in combination with ondansetron and dexamethasone against PONV. - DROPPOMB

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON31800

Enrollment

120

Registered

2007-12-14

Start date

2008-06-04

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative nausea and vomiting

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 18 years and older postoperative analgesia by means of a PCA pump with morfine

Exclusion criteria

Exclusion criteria: Pregnancy, breastfeeding, serious depression, bradycardia (

Design outcomes

Primary

Measure	Time frame
Primary endpoint is PONV yes or no. PONV is defines as at least one time vomited of nausea (verbal rating scale 2 or more) within 24 hours postoperative.	—

Secondary

Measure	Time frame
Secondary endpoints are PONV after 48 and 72 hours postoperative, number of times vomited, consumption of morfine, metoclopramide and ondansetron after 24, 48 and 72 hours postoperative and number of patients who develop delirium 72 hours postoperative.	—

Countries

Netherlands

Outcome results