Hyperfiltration hypothesis in children with a solitary functioning kidney: an assessment of glomerular function by single shot inulin clearance - THE KIMONO-STUDY

Hyperfiltration hypothesis in children with a solitary functioning kidney: an assessment of glomerular function by single shot inulin clearance - THE KIMONO-STUDY - KIMONO - kidney of monofunctional origin

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON31785

Enrollment

100

Registered

2008-12-31

Start date

2009-02-01

Completion date

Unknown

Last updated

2024-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

single kindey solitary functioning kidney

Interventions

None listed

Eligibility

Age

2 Years to 17 Years

Inclusion criteria

Inclusion criteria: - solitary functioning kidney - the child must be over 8 years of age - informed consent

Exclusion criteria

Exclusion criteria: none

Design outcomes

Primary

Measure	Time frame
Based on "Study design": Ad 1. Glomerular filtration rate (in ml.min/1.73m²), assessed by single shot inuline clearance Ad 2. Anthropometric data: waist-hip ration, subscapular skinfold thickness. Ad 3. Blood- and urine evaluation on concentrations of the following markers: plasma-renin activitiym ACE-polymorphisms, aldosterone, cystatin C, HbA1C, Von Willebrand-factor, cholesterol and homocystein.	—

Measure

Time frame

Based on "Study design": Ad 1. Glomerular filtration rate (in ml.min/1.73m²), assessed by single shot inuline clearance Ad 2. Anthropometric data: waist-hip ration, subscapular skinfold thickness. Ad 3. Blood- and urine evaluation on concentrations of the following markers: plasma-renin activitiym ACE-polymorphisms, aldosterone, cystatin C, HbA1C, Von Willebrand-factor, cholesterol and homocystein.

—

Secondary

Measure	Time frame
See primary study parameters/outcome of the study	—

Countries

Netherlands

Outcome results