chronic illness
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Utrecht
Eligibility
Age
2 Years to 17 Years
Inclusion criteria
Inclusion criteria: Age 8 to 18 years. Both prepubescent and pubescent children will be enrolled. • Healthy controls - will include any child without a history of disease or disability who are able to cooperate with the testing procedures. • Diagnosis of Juvenile Idiopathic Arthritis (JIA) - based on the ILAR criteria (56) OR • Diagnosis of Severe Hemophilia A or B (
Exclusion criteria
Exclusion criteria: Medical status that will not allow exercise testing Medications that interfere with heart rate response to exercise Non-ambulation: patients who are unable to ambulate Insufficient understanding of the Dutch language in both children and parents See also page 14 of the protocol
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameter is the agreement between predicted energy expenditure from accelerometry counts compared to directly measured energy expenditure via metabolic cart. | — |
Secondary
| Measure | Time frame |
|---|---|
| We will begin to develop disease specific prediction equations - where necessary - to determine the relationship between accelerometry counts and energy expenditure in these groups. We will compare 2 different accelerometers (Actical with Actigraph) to determine if one is superior in predicting energy expenditure compared to the other. | — |
Countries
Netherlands
Outcome results
None listed