gastric obstruction hypertrophic pyloric stenosis
Conditions
Interventions
None listed
Sponsors
Academisch Medisch Centrum
Eligibility
Age
2 Years to 11 Years
Inclusion criteria
Inclusion criteria: All children who present with hypertrophic pyloric stenosis will be included in the study
Exclusion criteria
Exclusion criteria: All children with associated diseases or malformations which may influence the assessed parameters will be excluded, as will patients who are not able to have oral feedings due to other pathology than hypertrophic pyloric stenosis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical parameters, 5-9 are seen as complications. 1. Time to full feeding= time from operation and the second full feeding that is tolerated(38) -This is done by the attending nurse to prevent bias by the surgeon. 2. Postoperative use of analgesics, defined as amount of dosage given during postoperative stay 3. Period of admission, after surgery defined in hours. 4. Duration of surgery, defined in minutes. 5. Perforations 6. Woundinfections of the skin: defined as redness of the skin with presence of a purulent discharge with or without a positive microbiological culture. 7. Dehiscence of the fascia 8. Delay in time to full feeding= any set back in feeding due to vomiting. 9. Incomplete pyloromyotomy (defined as: need for re-operation) 10. Scars are followed in time and conventional digital photographs are made direct postoperative, after 3 weeks and 6 months. | — |
Secondary
| Measure | Time frame |
|---|---|
| Immunological parameters. Parameters of the immune system include serum CRP, IL-1RA, IL-6. These parameters are measured before introduction of anaesthesia and 6, 24 and 48 hrs after surgery. IL-1RA and IL-6 are determined during operation every 15 minutes and just before skin incision. | — |
Countries
Netherlands
Outcome results
None listed