Sarcopenia in patients suffering from rheumatoid arthritis and osteoarthritis, a pilot study.

Sarcopenia in patients suffering from rheumatoid arthritis and osteoarthritis, a pilot study. - Sarcopenia and inflammation.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON31760

Enrollment

Registered

2008-01-21

Start date

2007-12-01

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

muscle weakness sarcopenia

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: rheumatoid arthritis osteoarthritis age 45-70 years

Exclusion criteria

Exclusion criteria: no

Design outcomes

Primary

Measure	Time frame
1. On a cellular level: differences in satellite cell number, proliferative potential of myoblasts, differential capacity of myoblasts, cellular capacity to react to the exposure to oxidative stress, presence of muscle atrophy. 2. On a systemic level: differences in the systemic inflammatory status, number of lymphocyte subsets. 3. On a functional level: differences in handgrip strength, leg press strength, isometric knee extensor strength. 4. On an imaging level: differences in muscle architecture.	—

Measure

Time frame

1. On a cellular level: differences in satellite cell number, proliferative potential of myoblasts, differential capacity of myoblasts, cellular capacity to react to the exposure to oxidative stress, presence of muscle atrophy. 2. On a systemic level: differences in the systemic inflammatory status, number of lymphocyte subsets. 3. On a functional level: differences in handgrip strength, leg press strength, isometric knee extensor strength. 4. On an imaging level: differences in muscle architecture.

—

Secondary

Measure	Time frame
No secondary outcome.	—

Countries

Netherlands

Outcome results