phantom auditory perception ringing in the ear
Conditions
Interventions
In the intervention group neuronavigated rTMS will be applied bilaterally to
the auditory cortices, which will be identified through a structural MRI scan.
Stimulation will be performed with 1Hz fre
Sponsors
Universitair Medisch Centrum Utrecht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Chronic non fluctuating tinnitus, demonstrated tinnitus by means of the Diagnostic Protocol Tinnitus UMCU, without a treatable cause of at least two months duration Age 18 years or older
Exclusion criteria
Exclusion criteria: Treatable cause of the tinnitus Use of anticonvulsant drugs or psychotherapeutic drugs which lower the seizure threshold History of epilepsy or family members with epilepsy Presence of active migraine Presence of structural brain changes Presence of psychiatric disease Presence of severe internal or heart diseases Metal objects in or around body that cannot be removed Metal workers Pregnancy (will be tested on the first day of TMS with a urine pregnancy test) Drugs or alcohol abuse Prior treatment with TMS
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameter is the tinnitus severity measured by the Tinnitus Questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary study parameter investigates whether (in case of positive results with rTMS) tinnitus characteristics (frequency, loudness, minimal masking level, residual inhibition) change. The change in these tinnitus characteristics will be measured with the tinnitus analysis | — |
Countries
Netherlands
Outcome results
None listed