anxiety disorders impaired stress responses
Conditions
Interventions
6. Interventions
6.1 Telemetry pill
All participants receive and ingest a telemetry pill (Vitalsense Minimitter,
size 2.3 x 0.87 cm) on the day of the TSST, at least 2 hours before commencing
the T
Sponsors
Universitair Medisch Centrum Utrecht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: healthy male students over 18
Exclusion criteria
Exclusion criteria: Exclusion criteria are: female gender, smoking more than 5 cigarettes a day, any psychiatric disorder, any significant medical condition including any gastrointestinal condition that would lead to a contraindication for the telemetric pill, participation in current psychological or psychopharmacological treatment, use of any medication which might influence autonomic response, including psychotropics, beta blockers, ACE inhibitors and any hormonal treatment. Acute exclusion criteria are: any acute illness, fever, having a severe cold, recent physical exertion within the last 2 hours, large meals.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 7. Outcome measures 7.1 Primary outcome measure The primary outcome measure is the reduction of the stress-induced hyperthermia response during/after the TSST. | — |
Secondary
| Measure | Time frame |
|---|---|
| 7. Outcome measures 7.2 Secondary outcome measures The Secondary outcome measures are - Blood pressure during the TSST - Correlation of saliva cortisol levels with the stress-induced hyperthermia response - Correlation of the stress-induced hyperthermia response and stress-inuduced blood pressure response with a set of anxiety/stress questionnaires | — |
Countries
Netherlands
Outcome results
None listed