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FSH receptor polymorphisms and treatment of poor responders

FSH receptor polymorphisms and treatment of poor responders - FSH receptor polymorphisms and treatment of poor responders

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON31719
Enrollment
112
Registered
2008-03-04
Start date
2007-08-01
Completion date
Unknown
Last updated
2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

poor response in assisted reproduction techniques (IVF/ICSI)

Interventions

None listed

Sponsors

Vrije Universiteit Medisch Centrum
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria are 2 ovaries in situ, less than 1,5 years between the two treatments, the use of a GnRH-agonist in the short protocol using 450 units of FSH, a minimum of one previous IVF or ICSI cycle in which the dosage FSH was less than 450 units of FSH (i.e. 225 or 300 IU/day), a long suppression protocol and a GnRH-agonist was used.

Exclusion criteria

Exclusion criteria: Exclusion criteria are removal of one ovary, more than 1,5 years between the treatments, the use of a GnRH-antagonist and no previous IVF/ ICSI cycle(s) or previous cycles in which the dosage was also 450 units of FSH or a short protocol was used.

Design outcomes

Primary

MeasureTime frame
-The FSH receptor polymorphism genotype. -The number of growing follicles and retrieved oocytes per treatment cycle.

Secondary

MeasureTime frame
Not applicable.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)