polycystic ovarian syndrome reduced fertility
Conditions
Interventions
None listed
Sponsors
Sint Elisabeth Ziekenhuis
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: PCOS or patients with a previous occurence of OHSS (ovarian hyperstimulation syndrome)
Exclusion criteria
Exclusion criteria: older than 38 years of age, early-follicular serum FSH over 10 IU/ml
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| * Nr, development and quality of embryos on day 3. | — |
Secondary
| Measure | Time frame |
|---|---|
| IVM treatment: * Nr of oocytes on day 0, after ovum pick-up. * Nr in vitro matured (MII) oocytes on day 1 (only visible with ICSI). * Nr of fertilised oocytes, pronucleï score. * Nr, development and quality of transfered embryos and cryopreserved embryos. pregnancy: * Result pregnancytest about 2 weeks after ovum pick-up. * Heartbeat by ultrasound, 6-8 weeks after ovum pick-up. * Follow up pregnancy partus: * Amenorrhoe * partus (spontaneous, sectio, forceps, vacuum) * Complications children: * Standard screening direclty after birth according to the Landelijke Verloskundige Registratie (LVR) * Follow up of children will be performed on several domains according to national and international standards. Shortly after birth, at 6 months, 1-, 2- and 5-years of age mental and motoric development will be scored according to national and international standards. | — |
Countries
Netherlands
Outcome results
None listed