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The protective effect of a nasal steroid (Fluticasone furoate) on exercise induced airway obstruction in cold air.

The protective effect of a nasal steroid (Fluticasone furoate) on exercise induced airway obstruction in cold air. - Icehall Studie

Status
Unknown
Phases
Phase 4
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON31652
Enrollment
91
Registered
2009-07-14
Start date
Unknown
Completion date
Unknown
Last updated
2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Exercise induced Airway obstruction Laryngeal hyperreactivity

Interventions

Children will receive placebo or 27,5 *g Fluticasone furoate in each nostril for 4 weeks.

Sponsors

Medisch Spectrum Twente
Lead Sponsor

Eligibility

Age
12 Years to 17 Years

Inclusion criteria

Inclusion criteria: children (12-17 years) with a history allergic rhinitis and/or allergic asthma able to perform lung-function FEV1>70% of predicted clinically stable for 3 weeks

Exclusion criteria

Exclusion criteria: Use of nasal/systemic steroids bronchodilators prior to test other cardiac or pulmonary disease signs of gastro-oesophagal reflux

Design outcomes

Primary

MeasureTime frame
Cold air exercise provocation test. Lungfunction will be determined with spirometric and oscillometric measurements.

Secondary

MeasureTime frame
Asthma Controle Questionnaire by Juniper Borg scale of dyspneoa

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)